Herb Wolfe is the acting chief medical officer and director for the Department of Homeland Security’s Office of Health Security (OHS), leading a whole-of-government approach to accelerate and expand R&D of current and new capabilities to enhance the security and resilience of the food and agriculture sector with recent completion of construction and commissioning of the highly anticipated National Bio and Agro-Defense Facility. Wolfe oversees medical, public health and workforce health and safety activities with responsibilities for CBRN health threats, border health security, food, agriculture and health resilience, total workforce protection, health informatics, regional medical operations and FSLTT health engagement. Prior to the establishment of OHS, Wolfe served as the Deputy Assistant Secretary for Health Security in the Countering Weapons of Mass Destruction Office. He joined DHS in September 2019 following a distinguished career in government service. Highlights include serving as Director for Medical and Public Health Preparedness Policy at the White House National Security Council and Chief Audit Executive for the U.S. Department of Veterans Affairs Veterans Health Administration. Before joining the VA, Wolfe was Senior Adviser to the Director at the Centers for Disease Control and Prevention’s National Center for Environmental Health and the Agency for Toxic Substances and Disease Registry, responsible for ensuring the department fulfilled its mission of using the best science in public health to prevent and mitigate harmful exposures and diseases related to toxic substances. In this role he was the senior CDC official deployed to Flint, Michigan, to lead the agency’s response to the drinking water public health emergency. Prior to his tenure at Health and Human Services, Wolfe served as a Technical Intelligence Officer at the Central Intelligence Agency and as the Director for Combating WMD at the United States Navy Office of the Surgeon General. From 1998 to 2002, Wolfe was a physician assistant in the U.S. Public Health Service, completing his family medicine residency at the Claremore Indian Hospital in Claremore, Oklahoma. He holds a PhD in biodefense and is considered an expert on global health security, public health, incident management, and biodefense. “DHS has a responsibility to defend the food, agriculture, and veterinary systems of the United States against intentional, accidental, and naturally occurring high-consequence events,” Wolfe said.